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Table of substrates, inhibitors and inducers (including This page is for educational use and thus is not intended to provide medical advice Cyp enzymes, clinical index drugs, transporters, and examples of clinical substrates, inhibitors, and inducers).

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For drug interaction purposes, the inhibitors and inducers of cyp3a metabolism listed above can alter serum concentrations of drugs that are dependent upon the cyp3a subfamily of liver enzymes, including cyp3a4, for elimination or activation. Several psychotropic agents are significantly impacted by cyp interactions or cause interactions by inhibiting or inducing cyp metabolism. List of cytochrome p450 modulators this is a list of cytochrome p450 modulators, or inhibitors and inducers of cytochrome p450 enzymes.

Cytochrome p450 (cyp450) are a group of enzymes encoded by the p450 genes and responsible for the metabolism of most drugs seen in clinical practice

90% of drugs are metabolised by cyp3a5, cyp3a4, cyp2d6, cyp2c19, cyp2c9 and cyp1a2. The following tables of cyp substrates, inhibitors, and inducers provide a perspective on drugs that are affected by, or affect, cytochrome p450 (cyp) enzymes Cyp substrate includes drugs reported to be metabolized, at least in part, by one or more cyp enzymes. Warfarin (major substrate of 2c9 & minor:1a2, 2c19 & 3a4 theophylline (major substrate of 1a2, 2e1 & 3a4